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5'nucleotidase (5'-ribonucleotide phosphohydrolase)
Elevated serum levels observed in hepatobiliary disease.
Specific
5'-nucleotidase domain-containing protein 1 (NT5DC1, NT5C2L1, LP2642)
5'-nucleotidase domain-containing protein 2 (NT5DC2)
7-methylguanosine phosphate-specific 5'-nucleotidase; cytosolic 5'-nucleotidase 3B; cytosolic 5'-nucleotidase III-like protein; cN-III-like protein (NT5C3B, NT5C3L)
cAMP-specific 3',5'-cyclic phosphodiesterase 4B; DPDE4; PDE32 (PDE4B, DPDE4)
CD73 (ecto-5'nucleotidase, 5-prime-ribonucleotide phosphohydrolase, NT5E)
cytosolic 5'-nucleotidase 1A (cN1A, NT5C1A)
cytosolic 5'-nucleotidase 1B; autoimmune infertility-related protein; cN1B (NT5C1B, AIRP, FKSG85)
cytosolic 5'-nucleotidase 3A; cytosolic 5'-nucleotidase 3; cytosolic 5'-nucleotidase III; pyrimidine 5'-nucleotidase 1; P5'N-1; P5N-1; PN-I; uridine 5'-monophosphate hydrolase 1; p36 (NT5C3A, NT5C3, P5N1, UMPH1, HSPC233)
General
nucleotidase
Properties
COMPARTMENT: cytoplasm
lysosome
plasma membrane
MOTIF: active site
N-linked HNK-I antigen
metal ion-binding site
Database Correlations
OMIM 129190
ENZYME 3.1.3.5
References
- Tietz Fundamentals of Clinical Chemistry 3rd ed, WB
Saunders, 1987 pg 412
- OMIM :accession 129190
- Schachner M, Martini R.
Glycans and the modulation of neural-recognition molecule function.
Trends Neurosci. 1995 Apr;18(4):183-91. Review.
PMID: 7539963 (HNK-I)